pAAVM41
AAV packaging plasmid expressing AAV2 Rep protein and AAVM41 capsid protein
AAVM41 capsid is a recombinant of AAV1, 6, 7, and 8 with a mosaic capsid surface and a conserved capsid interior.
AAVM41 was found more efficient than AAV6 in the heart and muscle, and was similar to AAV9 in the heart but weaker in the muscle. In fact, the myocardium showed the highest gene expression among all tissues tested in mice and hamsters after systemic AAVM41 delivery.
Yang, L., et al., A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection. Proc Natl Acad Sci U S A, 2009. Feb 20;106(10):3946–3951.
>pAAVM41
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