Recombinant adenovirus are used for achieving high levels of transgene expression in  various mammalian cell types, in which the vector remains as episomal DNA without integration into the host genome. High transduction efficiency and high levels of short-term gene expression make adenovirus as a preferred tool for in vivo gene delivery. Adenoviruses are often used in gene therapy and vaccination.

Nikebio has developed a series of proprietary technologies that have greatly improved recombinant adenovirus production protocols in terms of titer, purity, viability and consistency.

Adenoviral Vector Construction

We offer different adenovirus types and packaging systems and provide you with customized  adenovirus construction services.

Human Ad5 adenovirus: AdEasy system, AdMAX system.

Chimeric Ad5/F35 adenovirus:AdEasy system, the chimeric design of Ad5/F35 adenovirus.

Gutless adenovirus: AdEasy system, AdMAX system.

Available Scales for Adenovirus producing

ScaleApplicationTiterDeliverable
smallCell culture & in vivo≥1E+10 PFU/mL1E+10 PFU
MediumCell culture & in vivo≥1E+11 PFU/mL1E+11 PFU
Largein vivo≥1E+11 PFU/mL1E+12 PFU
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