Lentivirus (LV), derived from the Human Immunodeficiency Virus (HIV), are engineered RNA-based viral vectors. The critical advantage of lentivirus lies in their ability to integrate the exogenous genes into the host genome, ensuring long-term, stable gene expression. This feature renders them particularly useful for the generation of stable cell lines and is also a cornerstone in the realm of clinical immunocyte therapies.

VSV-G appeared to interact with ubiquitous cellular receptor, which conferred the ability of entry into multiple cell types tested and conferred high stability to the infectious vector particles.

Besides VSV-G, we supply you many different viral glycoproteins that have been incorporated into LVVs to improve their infectivity and confer them a more selective tropism.