Nanobody also known as single-domain antibodies (sdAb/VHH), are heavy-chain only antibodies that are naturally devoid of light chains, found in camelids such as llamas and in cartilaginous fish. They are widely used in tumor immunotherapy, cell therapy, and other research fields, owing to their excellent properties including high specificity, high stability, low immunogenicity, good affinity, high tissue penetration, and easy modification. As a result, nanobodies have received increasing attention from research organizations and pharmaceutical companies as promising next-generation therapeutic antibodies.

Nikebio offer one-stop custom nanobody services, including antigen preparation, llama/alpaca immunization, library construction, nanobody screening, expression, purification, and nanobody humanization services. This provides customers with comprehensive services for nanobody R&D and production.